Phospho-ATM/ATR Substrate Motif [(pS/pT) QG] MultiMab Rabbit mAb mix 6966S from Cell Signaling Technology

Product Specs
ItemPhospho-ATM/ATR Substrate Motif [(pS/pT) QG] MultiMab Rabbit mAb mix
CompanyCell Signaling Technology
Price Pricing Info Supplier Page View Company Product Page
Catalog Number6966S
Quantity100 µl
ApplicationsW, IP
ReactivityAll
HostRabbit
ClonalityMonoclonal
ModificationsX(s/t)QGX phosphate
Research AreaMotif Antibodies
TargetX(s/t)QGX phosphate
IsotypeIgG
CloneP-S/T2-100

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Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

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Website: http://www.cellsignal.com/

Website: Technical Support

(1) The ATM-E6AP-MASTL axis mediates DNA damage checkpoint recoveryeLifeSeptember 6, 2023Yanqiu Li, Feifei Wang, Xin Li, Ling Wang, Zheng Yang, Zhongsheng You, Aimin PengSer-139 (Cell Signaling Technology #9718S), phospho-ATM/ATR substrate motif (Cell Signaling Technology, #6966S), phospho-SMC1 Ser-957 (Cell Signaling Technology, #58052), phospho-CHK1 Ser-345 (Cell Signaling Technology,

(2) Syk-dependent alternative homologous recombination activation promotes cancer resistance to DNA targeted therapyResearch squareJune 9, 2023Zhou Q, Tu X, Hou X, Yu J, Zhao F, Huang J, Kloeber J, Olson A, Gao M, Luo K, et al.LC-lab. Syk inhibitor R406 was purchased from selleckchem. Syk(D3Z1E, 13198) antibody, anti-SQ/TQ motif (6966) and anti-pS345 Chk1 (2348) was purchased from CST. anti-CtIP (Thr847) (p1012–847, 1:2000), and anti-CtIP

(3) ATM signaling modulates cohesin behavior in meiotic prophase and proliferating cellsNature Structural & Molecular BiologyApril 1, 2023Zhouliang Yu, Hyung Jun Kim, Abby F. Dernburg(1:500, Thermo Fisher, cat no. MA1-23152), rabbit anti-pS/TQ antibody (1:500, Cell Signaling, cat. no. 6966), rabbit anti-COH-3/4 antibody (1:500, SDQ3972, ModENCODE project)118, rabbit anti-REC-8 antibody (1:500,

(4) ATM Regulation of the Cohesin Complex Is Required for Repression of DNA Replication and Transcription in the Vicinity of DNA Double-Strand BreaksMolecular cancer research : MCRMarch 1, 2023Bass TE, Fleenor DE, Burrell PE, Kastan MB.following antibodies were used: Phospho-ATM/ATR Substrate Motif (pS/TQ) (1:1,000; Cell Signaling, #6966), NIPBL (1:1,000; Santa Cruz, sc-374625), WAPL (1:1,000; Cell Signaling, 77428S), PDS5A (1:1,000; Bethyl

(5) Selective ablation of P53 in pancreatic beta cells fails to ameliorate glucose metabolism in genetic, dietary and pharmacological models of diabetes mellitusMolecular metabolismJanuary 1, 2023Uhlemeyer C, Müller N, Rieck M, Kuboth J, Schlegel C, Grieß K, Dorweiler TF, Heiduschka S, Eckel J, Roden M, et al.1:1000), rabbit anti P53 (#32532, Cell Signaling, 1:1000), rabbit anti pS/pT-ATM/ATR Substrate Motif (#6966, Cell Signaling, 1:1000), rabbit anti PDX1 (#5679, Cell Signaling, 1:1000), goat anti rabbit IgG –HRP

(6) R-loop-induced irreparable DNA damage evades checkpoint detection in the C. elegans germlineNucleic Acids ResearchAugust 12, 2022Tara Hicks, Emily Koury, Caleb McCabe, Cameron Williams, Caroline Crahan, Sarit SmolikoveProbes/Invitrogen, A32790, 1:500). Rabbit Phospho-ATM/ATR Substrate Motif [(pS/pT) QG] (Cell Signaling 6966S, 1:100), rabbitanti-OLLAS 1:1000 (A01658, Genscript). Rabbit anti-pCDK-1 (Cell Signaling 9111T, 1:500),

(7) Identification of a reciprocal negative feedback loop between tau-modifying proteins MARK2 kinase and CBP acetyltransferaseThe Journal of biological chemistryJune 1, 2022Tabassum Z, Tseng JH, Isemann C, Tian X, Chen Y, Herring LE, Cohen TJ.phosphorylated epitopes on immunoprecipitated CBP (1:4000, Cell Signaling #5759, #9477, #6967, #9614, and #6966),. Membranes were developed with ECL Western Blotting Substrate (ThermoFisher) and imaged using Image

(8) ATR inhibition enables complete tumour regression in ALK-driven NB mouse modelsNature CommunicationsDecember 1, 2021Joanna Szydzik et al.Cell Signaling Technology. Phospho-ATM/ATR Substrate Motif [(pS/pT) QG] MultiMab™ Rabbit mAb mix (#6966) was also from Cell Signaling Technology. Primary antibodies detecting SUN2 (ab124916, 1:5000), CD68

(9) UBQLN4 is an ATM substrate that stabilizes the anti-apoptotic proteins BCL2A1 and BCL2L10 in mesotheliomaMolecular oncologyDecember 1, 2021Liu F, Pan R, Ding H, Gu L, Yang Y, Li C, Xu Y, Hu R, Chen H, Zhang X, et al.performed with the following antibodies : anti‐UBQLN4 (Santa Cruz, sc‐136560, 1 : 1000), anti‐pSQ/TQ (CST, 6966, 1 : 1000), anti‐BCL2A1 (ABclonal, A0134, 1 : 500), anti‐BCL2L10 (ProteinTech, 18114‐1‐AP, 1 : 500),

(10) USP37 regulates DNA damage response through stabilizing and deubiquitinating BLMNucleic acids researchNovember 8, 2021Wu C, Chang Y, Chen J, Su Y, Li L, Chen Y, Li Y, Wu J, Huang J, Zhao F, et al.Santa Cruz Biotechnology. Anti-pT68-CHK2 (#2661), anti-CHK2 (#3440), anti–γH2AX (#9718) and anti-pS/TQ-ATM/ATR (#6966s) antibodies were obtained from Cell Signaling Technology. Anti-Histone H3(ab1791) and anti-ATM(ab32420)

(11) GPR68 Contributes to Persistent Acidosis-Induced Activation of AGC Kinases and Tyrosine Phosphorylation in Organotypic Hippocampal SlicesFrontiers in NeuroscienceMay 25, 2021Guokun Zhou, Xiang-ming ZhaCell Signaling Technology 9614S Phospho-(Ser/Thr)ATM/ATRSubstrate (rabbit) (S*/T*)QG, (S*/T*)Q 1:2,000 Cell Signaling Technology 6966S Phospho-(Ser) CDK Substrate (rabbit) (K/H)S*P 1:2,000 Cell Signaling Technology 8739S Phospho-(Ser/Thr)

(12) Divergent FUS phosphorylation in primate and mouse cells following double-strand DNA damageNeurobiology of diseaseDecember 1, 2020Johnson MA, Deng Q, Taylor G, McEachin ZT, Chan AWS, Root J, Bassell GJ, Kukar T.Bethyl Laboratories; A300-302A), phospho-ATR/ATM Substrate Motif [(pS/pT) QG] (1:1000; Cell Signaling Technologies; 6966), H2AX (1:1000; Millipore; AB10022), P-H2AX (1:1000; Millipore; 05–636), GAPDH (1:10,000; Cell Signaling Technologies

(13) Phosphorylation of seryl-tRNA synthetase by ATM/ATR is essential for hypoxia-induced angiogenesisPLoS biologyDecember 1, 2020Shi Y, Liu Z, Zhang Q, Vallee I, Mo Z, Kishi S, Yang XL.SerRS was detected with the rabbit polyclonal antibody against phosphor-ATM/ATR substrate (p-S*Q, #6966, Cell Signaling Technology) after IP by mouse monoclonal anti-SerRS antibody (1H4, #WH0006301M1, Sigma-Aldrich).

(14) Phosphoregulation of HORMA domain protein HIM-3 promotes asymmetric synaptonemal complex disassembly in meiotic prophase in Caenorhabditis elegansPLOS GeneticsNovember 11, 2020Aya Sato-Carlton, Chihiro Nakamura-Tabuchi, Xuan Li, Hendrik Boog, Madison K. Lehmer, Scott C. Rosenberg, Consuelo Barroso, Enrique Martinez-Perez, Kevin D. Corbett, Peter Mark CarltonESI-CID (Thermo Fisher). Phosphoenrichment antibodies were obtained from CST (catalog numbers 9607, 6966, 8139, 8738, 9624, 6967, 5759, 9942, 10001, 9614, 9477, 8134, 2325, 5243, and 3004). Protein assignments

(15) Phospho-Ser⁷⁸⁴-VCP Is Required for DNA Damage Response and Is Associated with Poor Prognosis of Chemotherapy-Treated Breast CancerCell reportsJune 9, 2020Zhu C, Rogers A, Asleh K, Won J, Gao D, Leung S, Li S, Vij KR, Zhu J, Held JM, et al.UFD1 (Bethyl, #A301-875A), CHOP (CST, #2895), BiP (CST, #3177), phospho-ATM/ATR substrate motif (CST, #6966), Pfn1 (CST, #3246), HIF1α (CST, #79233). Antibodies for immunofluorescence staining include BRCA1 (Santa Cruz

(16) Deciphering MET-dependent modulation of global cellular responses to DNA damage by quantitative phosphoproteomicsMolecular oncologyJune 1, 2020Bensimon A, Koch JP, Francica P, Roth SM, Riedo R, Glück AA, Orlando E, Blaukat A, Aebersold DM, Zimmer Y, et al.experiment. 2.3 Antibodies MET Tyr1234&1235 (#3077), NUMA1 Ser395 (#3429), phospho‐Ser/Thr‐Gln‐Gly (#6966), phospho‐Ser‐Gln (#9607), phospho‐Thr(Asp/Glu)X(Asp/Glu) (#BL4176), phospho‐Thr‐X‐Arg (#2351), CHEK1

(17) Nutrient-Driven O-GlcNAcylation Controls DNA Damage Repair Signaling and Stem/Progenitor Cell HomeostasisCell reportsMay 12, 2020Na HJ, Akan I, Abramowitz LK, Hanover JA.MA1–076, 1:50 dilution); rabbit phospho-ATM/ATR Substrate Motif [(pS/pT) QG] (Cell signaling, Cat# 6966S, 1:100 dilution); rabbit phospho-AKT (Cell signaling, CAT#9271S); rabbit phosphor-p44/42 MAPK (Erk1/2)

(18) ATM and P53 differentially regulate pancreatic beta cell survival in Ins1E cellsPloS oneJanuary 1, 2020Uhlemeyer C, Müller N, Grieß K, Wessel C, Schlegel C, Kuboth J, Belgardt BF.PARP1 (ab32064, Abcam); IκBα (4812, Cell Signaling); P21 (ab109199, Abcam); p-ATM/ATR Substrate Motif (6966, Cell Signaling); PDX1 (5679, Cell Signaling); p-IRE1α (NB1002323, Novusbio); pS139-H2A.X (9718, Cell Signaling

(19) CTCF cooperates with CtIP to drive homologous recombination repair of double-strand breaksNucleic acids researchSeptember 26, 2019Hwang SY, Kang MA, Baik CJ, Lee Y, Hang NT, Kim BG, Han JS, Jeong JH, Park D, Myung K, et al.Millipore, 1:2000 for IB), phospho-(serine/threonine) ATM/ATR substrate multi-monoclonal antibody (#6966S from Cell Signaling Technology, IB), BRCA1 (sc-642 from Santa Cruz, 1:1000 for IB), 53BP1 (NB100-305

(20) Oxidized ATM-mediated glycolysis enhancement in breast cancer-associated fibroblasts contributes to tumor invasion through lactate as metabolic couplingEBioMedicineMarch 1, 2019Kexin Sun, Shifu Tang, Yixuan Hou, Lei Xi, Yanlin Chen, Jiali Yin, Meixi Peng, Maojia Zhao, Xiaojiang Cui, Manran Liu1:800), AKT (4685, CST, 1:1000), p-AKT (12694 s, CST, 1:1000), GLUT1 (ab14683, abcam, 1:500), p-ST/Q (6966 s, CST, 1:1000), PKM2 (sc365684, Santa Cruz, 1:500), MCT4 (ab74109,1:1000), MCT1 (ab90582,1:1000) TGFβ1

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Phospho-ATM/ATR Substrate Motif [(pS/pT) QG] MultiMab ™ Rabbit mAb mix

Phospho-ATM/ATR Substrate Motif [(pS/pT) QG] MultiMab Rabbit mAb mix from Cell Signaling Technology

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Cell Signaling Technology

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Phospho-ATM/ATR Substrate Motif [(pS/pT) QG] MultiMab Rabbit mAb mix from Cell Signaling Technology

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